3-pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester
6-Pyrazol-1-yl-nicotinic acid methyl ester
CAS: 321533-62-4
Molecular Formula: C10H9N3O2
3-pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester - Names and Identifiers
3-pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester - Physico-chemical Properties
| Molecular Formula | C10H9N3O2 |
| Molar Mass | 203.2 |
| Density | 1.27±0.1 g/cm3(Predicted) |
| Boling Point | 330.8±27.0 °C(Predicted) |
| Flash Point | 153.8°C |
| Vapor Presure | 0.000163mmHg at 25°C |
| pKa | -0.42±0.19(Predicted) |
| Storage Condition | Inert atmosphere,Room Temperature |
| Refractive Index | 1.613 |
3-pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester - Risk and Safety
| Risk Codes | 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S3/9 - S36/37 - Wear suitable protective clothing and gloves. |
| HS Code | 29331990 |
3-pyridinecarboxylic acid, 6-(1H-pyrazol-1-yl)-, methyl ester - Introduction
acid methyl ester is an organic compound with the chemical formula C10H9N3O2. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: acid methyl ester is a colorless to pale yellow solid.
-Solubility: Soluble in organic solvents, such as ethanol and dichloromethane.
-Melting point: About 129-131 ° C.
-Stability: relatively stable at room temperature.
Use:
-acid methyl ester is a potential drug molecule that can be used in the field of medicinal chemistry research and drug development.
-It is used as an intermediate for the synthesis of other compounds, such as biologically active molecules.
-It can also be used as a catalyst in organic synthesis reactions.
Method:
-acid methyl ester can be obtained by synthetic reaction. A common synthetic method is through the condensation reaction of methylpyrazole-1-carboxylic acid with thionyl chloride as a primary amine (such as ethyldiphenylamine), it is then reacted with nicotinic acid to produce the target product.
Safety Information:
-the safety of acid methyl ester has not been fully evaluated and determined, so care should be taken when using and handling it.
-It may be irritating and damaging to the skin, eyes and respiratory system.
-Appropriate personal protective measures such as gloves, goggles and respiratory protective equipment should be taken during operation.
-It should be operated in a well-ventilated place and avoid inhalation or contact with its dust or vapor.
-Please refer to safety data sheets and other relevant safety information when using, storing and handling.
Nature:
-Appearance: acid methyl ester is a colorless to pale yellow solid.
-Solubility: Soluble in organic solvents, such as ethanol and dichloromethane.
-Melting point: About 129-131 ° C.
-Stability: relatively stable at room temperature.
Use:
-acid methyl ester is a potential drug molecule that can be used in the field of medicinal chemistry research and drug development.
-It is used as an intermediate for the synthesis of other compounds, such as biologically active molecules.
-It can also be used as a catalyst in organic synthesis reactions.
Method:
-acid methyl ester can be obtained by synthetic reaction. A common synthetic method is through the condensation reaction of methylpyrazole-1-carboxylic acid with thionyl chloride as a primary amine (such as ethyldiphenylamine), it is then reacted with nicotinic acid to produce the target product.
Safety Information:
-the safety of acid methyl ester has not been fully evaluated and determined, so care should be taken when using and handling it.
-It may be irritating and damaging to the skin, eyes and respiratory system.
-Appropriate personal protective measures such as gloves, goggles and respiratory protective equipment should be taken during operation.
-It should be operated in a well-ventilated place and avoid inhalation or contact with its dust or vapor.
-Please refer to safety data sheets and other relevant safety information when using, storing and handling.
Last Update：2024-04-09 20:49:11
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Product Name: Methyl 6-(1H-pyrazol-1-yl)pyridine-3-carboxylate Visit Supplier Webpage Request for quotation
CAS: 321533-62-4
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QQ: 3008007409
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CAS: 321533-62-4
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
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